Toxicity Testing

Sciore provides services for a wide range of toxicity and safety evaluation studies.

In vivo Testing

  1. Acute oral toxicity
  2. Acute dermal toxicity
  3. Acute inhalation toxicity
  4. Acute dermal corrosion
  5. Primary skin irritation
  6. Skin sensitization
  7. Mucous membrane irritation
  8. Sub-acute dermal toxicity (14 or 28 days)
  9. Sub-acute oral toxicity (14 or 28 days)
  10. Sub-chronic dermal toxicity (90 days)
  11. Sub-chronic oral toxicity (90 days)
  12. Chronic oral toxicity (180 days)
  13. One generation reproductive toxicity
  14. Acute systemic study (IV, IP, Oral, Dermal, Intramuscular)
  15. Sub-acute and chronic systemic toxicity
  16. Intracutaneous reactivity
  17. Occular irritation
  18. Penile irritation
  19. Vaginal irritation
  20. Rectal irritation
  21. Subcutaneous implantation (Acute, Sub-acute, Chronic)
  22. Muscle implantation (Acute, Sub-acute, Chronic)
  23. Bone implantation (Acute, Sub-acute, Chronic)
  24. Pyrogenicity 
  25. Pathogenicity 
  26. Dermal Pathology
  27. Potency
  28. Drug Bioassay as per IP, BP, USP
  29. Undue toxicity
  30. Abnormal toxicity
  31. Systemic toxicity as per USP guideline
  32. Safety Pharmacology

In vitro Testing

  1. Direct Cell Cytotoxicity
  2. Indirect Cell Cytotoxicity
  3. Chromosomal aberration
  4. Ames test (bacterial reverse mutation test)
  5. Hemocompatibility
  6. Pyrogenicity